Great shoe right out of the box. Most comfortable cushioning for walking (my primary purpose) of any I've had. Should have bought two pair!

It’s a comfortable shoe runs small I had to return them

Brooks Glycerin 22: A Game-changer

After 40 Years of Running! As someone who's logged countless miles over four decades in a wide array of running shoes—from ASICS Nimbus, Nike Pegasus, Vomero, and Invincible, to New Balance, Adidas, and Saucony—I can confidently say the Brooks Glycerin 22 is a true standout. This isn't just an incremental update; it's a monumental leap forward. The DNA LOFT v3 was just okay, but now nitrogen-infused, delivers a cushioning experience unlike anything I've ever felt. It's incredibly soft yet responsive, providing an amazing blend of comfort and energy return that has my feet thanking me on every run. Honestly, after being underwhelmed by the Glycerin 21 to the point of discarding them, the 22nd iteration is an absolute revelation. Brooks has truly hit a home run with this version. For those considering a pair, I highly recommend them. Just a note on sizing: while I typically wear a 29 cm (US men's 12), I found that going up to a 12.5 provided the perfect, comfortable fit. If you're seeking unparalleled comfort and a truly exceptional ride, the Brooks Glycerin 22 is, without a doubt, the best running shoe I've ever worn. Don't walk, run to get a pair!

Best For Cushioning

The best shoe in the Brooks line for cushioning and comfort.

I thought I would give them a try, I have had 4 pair of Ghost Max 2, which is my go-to and I guess will be ( I am aware of the Ghost Max 3 coming in August) The Glycerin 22 do not give me the comfort on the ball of my feet. I am currently deciding whether to return them, I am using an insert in them to alleviate my problem. I am an older walker, 30+ miles a week and loyal Brooks customer and realize my needs are in the minority but overall Brooks seem to suit my needs the best.